February 11th, 2009

I went to the doctor yesterday and he started me on new medications that I am not familiar with. I am on Lexapro, which is an antidepressant, Lamictal, which is a mood stabilizer, and Klonopin, which is for anxiety. I am a little leery about taking all of these medications but I would rather be totally numb than feel the way I’ve been feeling. This hopeless desperation is getting to be more than I can bear. I also have to go get blood work done and have a questionnaire that I have to fill out and take back next month. The Klonopin does not seem to do anything for the panic and it’s too soon for the others to have an effect. Maybe these will be the magic pills that finally make me feel better. Better living through chemistry. Right?

In other news, I finally got the house put back in order. I haven’t had the motivation to do anything for a while and after D left I suddenly started frantically looking for ways to make him come back or at least let me go to him. I know I am pathetic but he always complained about the house so I cleaned it top to bottom. I’m sending him pictures in the hope that he will see that I’m trying to make positive changes and that things would be better. He has said that once he gets settled I can come out there and we’ll take it from there. I want to make sure that it will not be the same dramatic, roller coaster disaster that our lives were before he left. I still miss him so much but having a goal to work towards and knowing that I will get to see him again makes me able to stand it a little more. I have always felt that things happen for a reason and maybe this had to happen so that I could worry about fixing myself instead of focusing on fixing my relationship. And I will do whatever needs to be done to get myself back together during this time.

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January 20th, 2009

“Foolproof Ways to Battle Anxiety

Tuning out your worries and improving your state of mind is easier than it sounds.

Rebecca Ruiz- Forbes
1.20.09

If the Dow just closed after a dismal day of trading and a tightening sensation is beginning to spread through your chest, stop and try this exercise:

Instead of focusing on the money you’ve already lost or obsessing over future losses, try zeroing in on the present moment. Let go of distractions like a looming bill or the record unemployment rate and concentrate on your breath. Take in all the air you can, pause and then release.

“It’s actually totally boring concentrating on your breath,” says Dr. Michael J. Baime, director of the Penn Program for Stress Management at the University of Pennsylvania Health System. “Lifting a barbell is totally boring too, but it’s exercising a muscle.” After 10 repetitions, he says, you should start to feel some degree of calm.

Though anxiety is the body’s natural response to a threat, that alarm system sometimes sounds unnecessarily, cluttering the mind with the chatter of negative thinking. The breathing exercise helps divert the mind’s attention elsewhere.

Controlled breathing isn’t the only strategy for anxiety relief, either. Others include engaging the brain and body, cognitive and behavioral adjustments and meditative techniques.

The Origins of Anxiety
If it’s difficult to understand why you are plagued by certain anxious thoughts, don’t take it personally–it’s a phenomenon that still eludes scientists. What is known, says Dr. Sonia Bishop, an assistant professor of psychology at the University of California, Berkeley, is that anxiety involves responses in two parts of the brain: the amygdala and the pre-frontal cortex.

The amygdala is responsible for the fight-or-flight response, while the pre-frontal cortex controls executive functions like decision-making and planning. A human foraging for berries, for example, would use the pre-frontal cortex to decide which berries to collect. If a predator suddenly jumped from the bushes, the amygdala would sound the alarm.

Scientists don’t fully understand why certain individuals are more prone to anxiety, but some theories suggest varying levels of neurotransmitters–the chemicals that relay signals between neurons and cells and affect how well the amygdala and pre-frontal cortex function–may play an important role.

What interests Bishop, however, is how the anxiety-ridden can reverse course regardless of pre-disposition. That’s why she recently conducted a brain-imaging study with 17 participants, some of whom had “high trait anxiety,” which was determined using a standardized measurement.

While being monitored by an MRI that tracks changes in brain activity, each participant had to engage the pre-frontal cortex by identifying certain letters and ignoring others. When the task increased in difficulty, both groups did well on recruiting that region of the brain. But when the task was easy, those with trait anxiety did a poor job. This was particularly telling, says Bishop, because the participants were not exposed to any anxiety-triggering threats.

The results have led her to believe that the anxiety-prone may have difficulty preventing the mind from lingering on distractions when performing easy, day-to-day tasks.

Though not yet tested by other scientists, Bishop’s conclusion seems to reflect what works well in other successful techniques for battling anxiety: meaningful distraction.

Overcoming Anxiety
You could try informally testing Bishop’s theory by doing a crossword puzzle instead of watching TV. More commonly accepted remedies for curbing anxiety include socializing and exercise, the latter of which can increase levels of dopamine, the body’s naturally occurring, mood-boosting chemical. Such distractions are most effective, though, when paired with a real effort to switch your focus.

In the simplest terms, that’s what Dr. Israel Liberzon,a professor of psychology and psychiatry at the University of Michigan, tries to teach his patients. Using cognitive and behavioral techniques, Liberzon shows patients–many of whom suffer from anxiety disorders–how to change the way they deal with their worries.

Often he advocates for reconsidering what you associate with anxiety, trying to judge perceived threats using a more rational scale or creating an emotional distance from certain fears. In other words, putting things in perspective.

But since that reaction is hardly intuitive, Liberzon recommends seeking out professional help. In addition to the Anxiety Disorders Association of America, a nonprofit organization that provides information on anxiety treatments, Liberzon says support groups and local universities with anxiety and stress research centers can serve as useful resources.

Like Dr. Bishop, Liberzon also recommends mindfulness meditation, a well-regarded technique that has been shown as effective in clinical settings. Mindfulness meditation emphasizes focusing on the present moment instead of dwelling on regrets or worries.

Dr. Baime, of the Penn Program for Stress Management, teaches dozens of these meditation techniques and says they can be learned by reading literature on the subject. He recommends Full Catastrophe Living: Using the Wisdom of Your Body and Mind to Face Stress, Pain and Illness by pioneer of mindfulness meditation Dr. Jon Kabat-Zinn, which Baime uses as a textbook in his classes.

Another alternative is to find local practitioners. While there is no certification process required to teach these methods, Baime says consumers can weed out potential snake-oil salesmen by asking to speak to previous students and inquiring about where the instructor learned the methods and how many students he or she has taught.

With the right tools, says Baime, mindfulness meditation can help the anxious reclaim their lives.

“When you learn to bring your attention into the present moment in a balanced way,” he says, “you learn to undo those negative predictions for the future.”"

9 Foolproof Ways To Deal With Anxiety (originally posted in Forbes)

“Try a Breathing Exercise

Instead of focusing on a looming bill or the record unemployment rate, take a moment to concentrate on your breath. Take in all the air you can, pause and then release. After 10 repetitions, you should start to feel some degree of calm, says Dr. Michael J. Baime, director of the Penn Program for Stress Management at the University of Pennsylvania Health System.

Mindfulness Meditation

Mindfulness meditation emphasizes focusing on the present moment instead of dwelling on regrets or worries. To learn more about it, try reading Full Catastrophe Living: Using the Wisdom of Your Body and Mind to Face Stress, Pain and Illness by Dr. Jon Kabat-Zinn, the pioneer of the subject. You can also find a local practitioner in your community, but be sure to speak to previous students and inquire about where the instructor learned the methods and how many students he or she has taught.

Engage Your Brain

The brain processes anxiety in two separate regions. The amygdala emits a fight-or-flight response while the pre-frontal cortex handles executive tasks like decision-making. A recent brain-imaging study showed that those prone to anxiety may have difficulty mediating their worries if not engaged in a task that requires diverting attention from the amygdala to the pre-frontal cortex. Though not yet replicated by other scientists, the findings reflect what works well in other successful techniques: high-quality distraction.

Socializing

Spending time with friends and family is not only a diversion from obsessing over the unknown, it can also improve your mood by forcing you to laugh or gain perspective on your fears and worries. During these rough times, socializing can also mean commiserating with your peers. But instead of collectively dwelling on the negative, try discussing positive developments.

Physical Activity

Exercise is another great diversion tactic. At a vigorous-enough pace, exercise can help produce increased amounts of the body’s naturally occurring, mood-boosting chemical dopamine. Getting active also gives people a sense of control and accomplishment, which can eclipse feelings of doubt and anxiety. There is one thing to remember, though: Be sure to focus on the task at hand instead of letting the mind wander.

Preventive Care

Anxiety is a powerful emotion that can overwhelm those who experience it. But instead of turning to alcohol, fatty food or television, try following the basic rules of good health and preventive care: stay physically active, eat well and get plenty of rest. Also avoid chemical substances like caffeine and nicotine, which can worsen anxiety, according to the Mayo Clinic.

Cognitive and Behavioral Techniques

Dr. Israel Iberzon,a professor of psychology and psychiatry at the University of Michigan, uses cognitive and behavioral techniques to help his patients overcome anxiety. These include “changing the narrative” associated with the anxiety, creating emotional distance and assessing the threat with a new perspective. Since these reactions are hardly intuitive, Iberzon recommends seeking out professional help to better understand them.

Psychotherapy

Therapy can be an effective tool for those who want to learn more about cognitive and behavioral coping techniques, but it may also be necessary for those who have a clinical disorder. Anxiety disorders, according to the nonprofit organization Anxiety Disorders Association of America, are the most common illnesses in the U.S. A psychotherapist can make an official diagnosis and provide support and treatment.

Anti-anxiety and Anti-depressant Medications

Prescription medicine can alleviate symptoms of a clinical anxiety disorder. For short-term relief, patients can take benzodiazepines, which work as sedatives. Anti-depressants like duloxetine (Cymbalta) and fluoxetine (Prozac) have also been used to treat anxiety disorders, according to the Mayo Clinic. A new study in the Journal of the American Medical Association found that the anti-depressant Lexapro was very effective in treating adults with Generalized Anxiety Disorder over the age of 60.”

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January 4th, 2009

Expectant Brains Help Predict Anxiety Treatment Success
A network of emotion-regulating brain regions implicated in the pathological worry that can grip patients with anxiety disorders may also be useful for predicting the benefits of treatment.
ScienceDaily - Jan. 4, 2009

A new study appearing online Jan. 2 reports that high levels of brain activity in an emotional center called the amygdala reflect patients’ hypersensitivity to anticipation of adverse events. At the same time, high activity in a regulatory region known as the anterior cingulate cortex is associated with a positive clinical response to a common antidepressant medication.

The study will appear in an upcoming issue of the American Journal of Psychiatry.

For individuals with anxiety disorders, the anticipation of a bad outcome can be worse than the outcome itself, says Jack Nitschke, assistant professor and clinical psychologist at the University of Wisconsin-Madison School of Medicine and Public Health and lead author of the new study. Some individuals spend so much time worrying about getting into a negative situation or having a panic attack, he says, that the condition becomes debilitating. “In an extreme situation, they might not even leave their home,” he says.

To study how the brain responds to anticipation, researchers at the UW-Madison Waisman Laboratory for Brain Imaging and Behavior used functional magnetic resonance imaging (fMRI) to examine patients with generalized anxiety disorder (GAD) as they viewed a set of negative and neutral images. Patients were shown pre-image cues several seconds before each picture so they would know what to expect: a circle before a neutral image and a minus sign before an aversive image.

While GAD patients showed no difference compared to healthy subjects in brain activation in response to the aversive or neutral pictures themselves, they displayed unusually high levels of amygdala activity in response to both anticipatory cues. According to Nitschke, the response suggests that the patients are hypersensitive to the anticipation of any stimuli, even those they are told will not be negative.

“In response to both of those anticipatory signals, the GAD subjects — the anxious folks — are showing huge amounts of amygdala activation that is much more than what healthy control subjects showed,” he says.

The researchers believe the high levels of amygdala activity seen in GAD patients reflects an indiscriminate and disproportionately large response to the idea that something negative might happen in the future, even in a lab setting where they know nothing bad will actually occur, he says.

“It suggests that there are differences in anticipatory brain processing in these individuals,” he says, adding that the result has important implications for other related disorders as well. “That’s the crux of what’s debilitating in people with anxiety disorders, whether it’s panic disorder, obsessive compulsive disorder or post-traumatic stress disorder.”

The patterns of brain activity also appear to hold predictive power for how patients will respond to treatment for their anxiety. After their brain scans, the GAD patients in the study received an eight-week course of treatment with venlafaxine (Effexor), a common antidepressant. Clinical improvement on the medication was associated with higher levels of pre-treatment brain activity in the anterior cingulate cortex (ACC) in anticipation of both aversive and neutral stimuli.

The ACC is a regulatory brain region important for modulating emotional responses. Activity in the same area has been shown to predict clinical outcome in patients with depression.

“When you look within the GAD patient population, that area is what predicts whether they respond to this treatment,” says Nitschke. “What it suggests is that people who still have some residual functioning of that area are the people who are more likely to get better” with this drug.

Choosing the most appropriate treatment approach for an individual patient is an important and difficult issue, he says, because anxiety disorders encompass a range of conditions with diverse symptoms and causes. Anxiety disorders are also frequently associated with depression, and Nitschke and his collaborators next plan to examine GAD patients with and without major depressive disorder.

“This is a critical new direction that the field is already moving in — using fMRI to predict treatment response,” he says. “Hopefully we’ll be able to use that eventually to determine what kind of treatment to provide to people.”"

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December 3rd, 2008

“Nearly 5 Percent Of U.S. Population Suffers From Persistent Depression Or Anxiety

Science Daily - 12-3-2008

Though effective treatments are available for individuals suffering from chronic depression and anxiety, very little is known about how often these treatments are used or how prevalent these conditions are among the nation’s general population.

But in a first-of-its-kind study, UCLA researchers have developed estimates for both the prevalence of chronic psychiatric illness in the general population and how often individuals suffering from such illnesses receive appropriate treatment.

In the study, published in the December issue of the peer-reviewed journal Psychiatric Services and currently available online, researchers found that approximately 4.7 percent of the nation’s population suffers from persistent depression or anxiety disorders, with a minority of those afflicted receiving adequate medication or counseling.

“From a policy perspective, this study indicates that we have to do much better in terms of helping people in the population and clinicians in primary care,” said lead author Dr. Alexander S. Young, a UCLA professor of psychiatry and director of health services for the Department of Veterans Affairs Desert Pacific Mental Illness Research, Education and Clinical Center (MIRECC). “We need to understand that psychiatric disorders are treatable with psychotherapy and/or medication. Patients would benefit if we improved linkages between primary care and specialty mental health care so that patients are referred and accept referrals to mental health specialists, especially when they are chronically ill.

“Also, we have to improve insurance arrangements so that they encourage more intensive treatment in people who remain ill,” he said.

The study was based on data from Healthcare for Communities, a nationally representative household survey of adults in the United States. The researchers analyzed responses from 1,642 adults with major depression or anxiety disorders. These surveys, conducted in 1997 and 1998, with follow-ups approximately two-and-a-half years later, assessed diagnosis, quality of life, treatment satisfaction, medical conditions, suicidal thoughts, insurance, and the use of medications and counseling.

At follow-up, the researchers found that 59 percent of the individuals no longer met the criteria for having a psychiatric disorder. But to their surprise, they found that among those who remained ill, there were only modest increases in medication use and no statistically significant increase in the use of counseling for their disorders — measures that are known to significantly improve outcomes, especially when used in combination. Among this subgroup:

  • 87 percent had a chronic, co-morbid medical disorder.
  • In the prior year, 88 percent had seen a primary care practitioner, but only 22 percent had consulted a mental health specialist.
  • In the two-and-a-half years between baseline and follow-up, use of medication rose from 21 percent to 29 percent, and use of counseling fell from 23 percent to 19 percent.
  • Only 12 percent with persistent illness were getting both medication and counseling (the appropriate treatment in this situation).
  • 51 percent had suicidal thoughts at follow-up.
  • Men and those with less education received less treatment.

“Persistent depressive and anxiety disorders are remarkably common in the U.S. population and are associated with substantial morbidity. There are significant problems with the quality of care received by this population, and these problems persist over time,” the researchers concluded. “In the population with persistent depressive and anxiety disorders, increasing the rate of appropriate care from its current low level could result in substantial improvement in individuals’ lives.”

In addition to Young, study authors included Ruth Klap, Ph.D., of the Health Services Research Center at UCLA; Rebecca Shoai, M.P.H., M.S.W., affiliated with MIRECC; and Kenneth B. Wells, M.D., M.P.H., of the UCLA Department of Psychiatry and the RAND Corp.

The Robert Wood Johnson Foundation funded the study, with additional support from the National Institute of Mental Health and the U.S. Department of Veterans Affairs.”

Adapted from materials provided by University of California - Los Angeles.


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December 2nd, 2008

Another woman comes forward with her story of dealing with panic attacks. In my opinion it tends to strike the most stable, normal people you can imagine; such as this woman. When your entire life seems to coast along, blessed at every turn, you’re mind is not prepared for an overload of stress and responds by sending your body into a state of shock equal to that of what you are going through both mentally and emotionally.

From Times Online
November 17, 2008
High anxieties - presenter Anna Williamson on coping with panic attacks
The GMTV presenter Anna Williamson, 25, describes how she coped when her life fell apart and she found herself living in a cycle of fear

Hilary Freeman

I’ve always been an oversensitive perfectionist. My family used to call me “Miss 35″ because, at 11, I acted so much older than my years. But I thought of myself as a strong, pragmatic person who didn’t have any problems dealing with stress.

Perhaps that’s why when I did develop an anxiety disorder I found it so hard to accept that I’d lost control.

It was just over a year ago that things started to unravel. In addition to my regular work on GMTV, I’d taken on a theatre job, a role in a pantomime in Brighton. I found myself working 16-hour days, seven days a week, and also commuting between London and Brighton.

Knowing how lucky I was to have both jobs, I felt that I had to put 100 per cent into them.

I coped fine for the first few weeks, but then I started to feel unable to apply myself to anything properly. I hardly saw my partner and I felt guilty because I couldn’t give any time to my friends or family. So, instead of sleeping, any spare time I had was spent catching up with friends, people-pleasing to the detriment of my own mental health. I didn’t enjoy socialising and I’d wake up feeling as if I’d been run over by a bus. I’d lie in bed with lines and songs and camera directions going round and round in my head.

I’d lie in bed worrying about irrational things Nobody at work could tell that I wasn’t coping. Somehow, I’d get through the day. But, at home, in the evenings, I’d find myself bursting into tears for no reason at all. I couldn’t understand why, when I was doing what I’d always wanted to do, I was feeling so awful, so isolated. My mother was concerned and told me to rest. Instead of taking heed, I tried to protect her. I told her I was fine; I would even go round to my parents’ house and do the washing-up, to “prove” how well I was coping.

I made it through the panto run and at the end of January I went on holiday to Thailand with my boyfriend. Usually, I love travelling, but this time I felt dreadfully homesick. I found it difficult to get to sleep and I’d lie there worrying about the most irrational things. What if we get hit by a tsunami? What if a spider comes into the room? Or a snake? What if something happens to my family? I was relieved when dawn came and I could get up, so I’d no longer be alone with my thoughts. For the first time, I didn’t come back refreshed from my holiday.

Things got easier for a few months, but of course I hadn’t really dealt with anything. And by the summer I felt myself losing control again. My relationship was starting to break down and I was also anxious about family problems: cancer was diagnosed in my elder brother’s girlfriend and my younger brother was suffering from panic attacks (there’s some evidence that anxiety disorders can run in families).

I started to obsess about work, learning lines several days early instead of relaxing. I worried about my friends; I’d think, “I haven’t called that person for ages, they must think I’m a rubbish friend”. I worried about my parents, who were upset about my brothers, and, of course, I worried about my brothers, too.

Most people have at least one panic attack

All that anxiety built up inside me. I suppose it was inevitable that it had to come out somehow. And at the end of September 2006, come out it did, in the form of panic attacks. The first one happened at a friend’s house, in the middle of the night. For anyone who hasn’t had a panic attack - and most people will experience at least one in their lifetime - they are extremely frightening. The sensation starts in your chest. It’s like someone’s prodding a hot poker into your breastbone. Then your chest feels tight and fluttery, you start to hyperventilate, your heart begins to palpitate and you can feel your pulse thudding in your ears.

Suddenly you feel ultra alert, your eyes are very wide, and a hot, then cold, wave spreads across your body. You can’t breathe. You really believe you’re going to die.

After that first attack, I found myself in a cycle of fear. I was so frightened of having another that I became even more anxious and the attacks started to occur regularly. Over the next two months I had one almost every day.

Finally, on November 1, I lost it at work. I’d felt totally exhausted from the moment I’d woken up and I’d also had an argument with my partner. I was in the studio, shortly before going on air, and I began to feel like I was going to faint. A colleague asked if I was all right and I just burst into tears: great big, heaving sobs that I couldn’t control. I couldn’t breathe.

I felt completely unable to go on. I was sent home and signed off work. At first, I couldn’t stop crying and I couldn’t bear to be left alone. I was terrified that I’d lose my job, even though everyone had been very understanding. The doctor put me on beta-blockers, but they didn’t help.

I had to learn to relax

Then a friend recommended a consultant psychiatrist who specialised in hypnosis and I went to see him privately. He prescribed a mild antidepressant and told me that if I was to get over the panic attacks, I needed to change my outlook. I had to learn to relax and to stop worrying about other people.

For the first time, I unloaded all my anxieties and talked openly about how I felt. Using hypnosis - a deep state of relaxation - he took me back to my first attack and taught me to deal with my worries by storing them away in my head so that they no longer frightened me.

Within three weeks I was back at work, and I haven’t had another attack since. Of course, I still feel anxious and have sleepless nights. But by using hypnosis CDs and practising the techniques that the psychiatrist taught me, I’m able to get my anxieties back under control so that they don’t take over. If I
start worrying, I focus on positive thoughts: “Everything’s fine”, “I’m a very lucky girl”, etc.

I’ve also taken up Pilates, which helps me to relax and to breathe better.

Although my partner was very supportive, I felt that I needed to be on my own and I ended the relationship. I’m starting to appreciate having time to myself and enjoying my own company. I no longer go out when I’m too tired, just to please my friends. I’ve learnt to say no. I also plan in advance so that my workload doesn’t overwhelm me.

Hypnosis worked for me but it isn’t the only answer. Drugs, relaxation techniques and therapy can also work. The worst thing that you can do is to try to cope alone.

Press the panic button

According to the mental health charity, Mind (www.mind.org.uk), a panic attack is an exaggeration of the body’s normal response to fear, stress or excitement.

A spokesperson for Mind says: “When faced with a situation seen as potentially threatening, the body automatically gears itself up for danger, by producing quantities of adrenalin for ‘fight or flight’. This would have prepared our cave-dwelling ancestors to fight or to run away from danger, but it’s much less appropriate to the stresses that we encounter today.”

Adrenalin floods the body, causing the muscles to tense, the heart to beat rapidly, and faster breathing. Other symptoms include increased sweating and higher sensory alertness.

Panic attacks can come on very quickly and last for between five and 20 minutes.

You may have one or two panic attacks and never experience another. Or you may have attacks once a month or several times each week. ”

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